Gilbert Ling in 1962
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Dear colleagues,
I'm very proud to have this opportunity to address the participants of
the Congress.
Fourteen years ago, I put up a Website (www.gilbertling.org)
bearing the title "Science Cannot Cure Cancer and Aids without your
help". Despite advanced technology at our disposal, we are getting too
little because the version of cell physiology probably is not
unequivocally true now as more than half a century ago.
I had been able to introduce a unifying new theory of life phenomena
half a century ago in monograph entitled "A
Physical Theory of the Living State, the Association-Induction (AI)
Hypothesis". For the AI Hypothesis represents a transformation from
Macroscopic view of life phenomena in terms of untenable
semi-permeability and rigid membrane pores to a Microscopic
story of auto-cooperativity and nano-protoplasm.
If I am not mistaken, one of the most urgent problems that you and other
responsible leaders of the Congress are in a position to fight
effectively is to get the young generations of future bio-medical
scientists to arm themselves with the correct new cell and below-cell
physiology. And for that we also urgently need informed and dedicated
teachers.
To help those teachers I made a special effort by writing another book "Life
at the Cell and Below-Cell Level" (Pacific Press, 2001). The AI
hypothesis did not come from nowhere. Among the important contributions
are those from Soviet scientists like Dmitri
Nasonov and Afanasiy Troshin of the
Leningrad Institute of Cytology.
Dr. Alexander Malygin
from the Pavlov Institute of Physiology in close cooperation with
Dr. Vladimir Matveev
successfully translated my fourth
book into Russian and put it on the market.
I hope that Congress will help to fight and vanquish not only cancer and
AIDS but even deeper threats to Mankind's future generations will face
sooner than later.
I wish you great successes on this way.
Gilbert Ling
2012-May
Уважаемые коллеги!
Я очень горжусь тем, что имею возможность обратиться к участникам
конгресса.
Четырнадцать лет назад на своем веб-сайте (www.gilbertling.org)
я опубликовал призыв «Наука не может вылечить рак и СПИД без вашей
помощи". Несмотря на имеющиеся в нашем распоряжении передовые
технологии, мы достигли в этом направлении слишком мало, потому что
современная версия физиологии клетки, вероятно, не столь однозначно
верна сегодня, как и более полувека назад.
В 60-е годы я впервые предложил объединяющую теорию феномена жизни в
монографии "Физическая
теория состояния жизни: гипотеза ассоциации-индукции" (АИ). Эта
гипотеза представляет собой переход от макроскопического
воззрения на жизненные явления в терминах полупроницаемости и жестких
мембранных пор к рассмотрению микроскопических явлений
в клетке на базе рассмотрения свойств авто-кооперативности и
нано-протоплазмы.
Если я не ошибаюсь, одна из наиболее актуальных проблем, с которыми вы и
другие лидеры Конгресса в состоянии эффективно
бороться, это воспитание молодого поколения ученых в биомедицинских
дисциплинах, вооруженных правильной клеточной и субклеточной
физиологией. А для этого нам также срочно необходимы современные и
преданные своему делу преподаватели.
Чтобы помочь такому обучению, я приложил особые усилия в написании
другой книги "Жизнь
в клетке и на субклеточном уровне" (Pacific Press, 2001). Гипотеза
АИ не пришла из ниоткуда. Важнейший вклад внесли в нее такие советские
ученые, как Дмитрий Николаевич
Насонов и Афанасий
Семенович Трошин из ленинградского Института цитологии.
Сегодня д-р Александр
Вячеславович Малыгин из Института физиологии
им. Павлова в тесном сотрудничестве с д-ром
Владимиром
Васильевичем Матвеевым из Института цитологии успешно
перевели эту мою четвертую книгу на
русский язык и предложили ее
для преподавателей, студентов и других заинтересованных читателей.
Я надеюсь, что результаты работы Конгресса помогут бороться и побеждать
не только такие болезни как рак и СПИД, но и более глубокие угрозы, с
которыми будущие поколения человечества столкнутся рано или поздно.
Я желаю вам больших успехов на этом пути.
Гильберт Линг
Май 2012
Gilbert Ling's books:
1. Ling, G.N.
A Physical
Theory of the Living State: The Association-Induction
Hypothesis, Waltham, Massachusetts: Blaisdell, 1962. 680
p.
2. Ling, G.N.
In Search of the Physical Basis of Life,
New York and London: Plenum Press, 1984. 791 p.
3. Ling, G.N.
A Revolution in the Physiology of the Living
Cell, Malabar, Florida: Krieger
Publishing Company, 1992. 404 p.
4. Ling, G.N.
Life at the Cell and Below-Cell Level: the Hidden
History of a
Fundamental Revolution in Biology.
Книга переведена на русский язык.
Main principles of Ling’s physical theory of the living cell
"A PHYSICAL THEORY OF THE LIVING STATE:
the Association-Induction Hypothesis with Considerations
of the Mechanisms Involved in Ionic Specificity, Behavior
of Proteins, Selective Accumulation of Ions and
Nonelectrolytes, Cellular Electrical Potentials, Ionic
Permeability and Diffusion, Excitation and Inhibition,
Contractile Mechanism, Enzyme Action, Drug and Hormone
Action, Antibody-Antigen Reaction, Fertilization,
Chemical Embryology, Growth, Differentiation, and
Cancer."
GILBERT N. LING
"Ling offers no less than... a general molecular
theory of life phenomena... a major synthesis, moving
from the minor variables at the molecular level to the
major properties of the cellular level... Such an
integrative and synthetic treatment cannot fail to give
the whole field of biology a great forward impetus."
RALPH W. GERARD, University of Michigan
"At a time when we look forward to the merging of
the physical and biological sciences, this is a most
stimulating book, distinguished by a bold and inquisitive
attitude on the one hand, and careful experimental
methods on the other."
C.N. YANG, Nobel Laureate in Physics, 1957
GILBERT N. LING, born in 1919, a native of China, entered
the National Central University in Chungking as a student
of animal husbandry. After two years, he transferred to
the biology department and received a B.Sc. degree in
1943. Having done graduate work in zoology at the Tsing
Hua University in Kunming, he won the Boxer Indemnity
Fellowship, in 1945, to study physiology in the United
States. In 1948, he received his Ph.D. degree in
physiology from the University of Chicago, where he had
studied under Dr. Ralph W. Gerard.
Since that time, Dr. Ling has been engaged, without
interruption, in research while successively holding the
positions of Seymour Coman Post-Doctoral Fellow at the
University of Chicago, Instructor at the Johns Hopkins
School of Medicine, Assistant and Associate Professor at
the University of Illinois School of Medicine, and Senior
Research Scientist at the Eastern Pennsylvania
Psychiatric Institute. Dr. Ling is presently Director of
the Department of Molecular Biology at Pennsylvania
Hospital.
***
IN SEARCH OF THE
PHYSICAL BASIS OF LIFE
GILBERT N. LING
Pennsylvania Hospital, Philadelphia, Pennsylvania
"The image [of science] has been previously drawn...
from the study of finished scientific achievements as
these are recorded in the classes and more recently in
the textbooks... Inevitably... a concept of science drawn
from them is no more likely to fit the enterprise that
produced them than an image of national culture drawn
from a tourist brochure or language text."
Thomas Kuhn, The Structure of Scientific
Revolutions
Any scientific investigation is an open-ended, ongoing
process that must continually reevaluate past decisions
and build and expand upon new theories and research
findings. In Search of the Physical Basis of Life
chronicles the history of scientific efforts to
understand the living cell - the basic unit of all life -
and presents the foundation of a new paradigm in cell
physiology, the association-induction (A-I) hypothesis.
Dr. Ling's monumental treatise considers the rise to
dominance of the membrane pump theory and then builds a
solid framework for the A-I hypothesis, citing the
reasons that led to its brief introduction in 1952 and a
detailed version ten years later. The A-I hypothesis
suggests that cellular ions are adsorbed on anionic
protein side chains and that intracellular water is
adsorbed in multilayers on polypeptide chains in the
cell, so that the components of a cell exist in a
dynamically ordered and functionally coherent array. In
addition to the historical and theoretical development of
the A-I hypothesis, Dr. Ling presents results of the
extensive worldwide testing of alternate theories that
has been carried out over the past thirty years.
Distinguished by its all-inclusive approach to a science
that reaches across the natural boundaries of time and
the man-made boundaries of specialized fields, this
unique volume synthesizes old and new information of
great overall significance.
For those who anticipate that progress in cell physiology
may soon match that in genetics and for those who simply
need a more useful set of basic concepts in bio-logical
and medical research, this book is a must.
***
A REVOLUTION IN THE PHYSIOLOGY
OF THE
LIVING CELL
GILBERT N. LING
Full text PDF
"Dr. Ling's work is sophisticated and essential. This book will
guide its readers to the new era of genuine biology."
Dr. Hiroshia Tamagawa, Gifu University, Gifu, Japan
***
LIFE AT THE CELL AND BELOW-CELL LEVEL.
THE HIDDEN HISTORY OF A FUNDAMENTAL REVOLUTION IN BIOLOGY
GILBERT N. LING
"Life on earth is in increasing danger. In my view, if
Gilbert N. Ling's association-induction hypothesis is widely taught to
the younger generation, we could have a much better chance
to save
life on earth".
Prof. Miklós
Kellermayer, University of Péch, Péch,
Hungary
Some important Gilbert Ling's articles in PDF format
are available here:
Physiological
Chemistry and Physics and Medical NMR
Last publication:
Ling G.N.
A Convergence of Experimental and Theoretical Breakthroughs Affirms the
PM theory of Dynamically Structures Cell Water on the Theory's 40th
Birthday. In: Water and the Cell. (Pollack G.H., Cameron I.L. and
Wheatley D.N., eds.). Springer, 2006, p. 1-52.
List of Ling's
papers
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